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DESCRIPTION
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DESCRIPTION
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Package: EWCE
Type: Package
Title: Expression Weighted Celltype Enrichment
Version: 1.15.0
Authors@R:
c(person(given = "Alan",
family = "Murphy",
role = c("cre"),
email = "[email protected]",
comment = c(ORCID = "0000-0002-2487-8753")),
person(given = "Brian",
family = "Schilder",
role = c("aut"),
email = "[email protected]",
comment = c(ORCID = "0000-0001-5949-2191")),
person(given = "Nathan",
family = "Skene",
role = c("aut"),
email = "[email protected]",
comment = c(ORCID = "0000-0002-6807-3180")))
Description: Used to determine which cell types are enriched within gene lists. The package
provides tools for testing enrichments within simple gene lists (such as human disease
associated genes) and those resulting from differential expression studies. The package does
not depend upon any particular Single Cell Transcriptome dataset and user defined datasets
can be loaded in and used in the analyses.
URL: https://github.com/NathanSkene/EWCE
BugReports: https://github.com/NathanSkene/EWCE/issues
License: GPL-3
Depends: R (>= 4.2),
RNOmni (>= 1.0)
VignetteBuilder: knitr
Imports:
stats,
utils,
methods,
ewceData (>= 1.7.1),
dplyr,
ggplot2,
reshape2,
limma,
stringr,
HGNChelper,
Matrix,
parallel,
SingleCellExperiment,
SummarizedExperiment,
DelayedArray,
BiocParallel,
orthogene (>= 0.99.8),
data.table
Suggests:
rworkflows,
remotes,
knitr,
BiocStyle,
rmarkdown,
testthat (>= 3.0.0),
readxl,
memoise,
markdown,
sctransform,
DESeq2,
MAST,
DelayedMatrixStats,
ggdendro,
scales,
patchwork
biocViews: GeneExpression, Transcription, DifferentialExpression,
GeneSetEnrichment, Genetics, Microarray,
mRNAMicroarray, OneChannel, RNASeq,
BiomedicalInformatics, Proteomics, Visualization,
FunctionalGenomics, SingleCell
RoxygenNote: 7.3.1
Encoding: UTF-8
Config/testthat/edition: 3